A common anti-inflammatory drug has been found to be an effective antiviral agent in the treatment of mild and moderate Covid-19 patients. The drug, indomethacin, is widely used to treat various types of inflammation-related conditions. The study on Covid patients, by IIT Madras, has been published in Nature Scientific Reports.
THE DRUG: Indomethacin is a non-steroidal anti-inflammatory drug available as capsules and a liquid suspension, to be taken orally. According to the US National Library of Medicine, indomethacin works by stopping the body’s production of a substance that causes pain, fever, and inflammation. It is used to relieve moderate to severe pain, tenderness, swelling, and stiffness caused by various kinds of arthritis, and pain in the shoulder caused by inflammation.
The findings: A randomised clinical trial was conducted by IIT Madras researchers at Panimalar Medical College and Research Institute, Chennai. Out of 210 patients admitted, 107 were randomly allocated to a control group and treated with paracetamol and standard care, while 103 patients were administered indomethacin along with standard care of treatment, a media release from IIT Madras said.
A UK patient with a severely weakened immune system had Covid-19 for almost a year and a half, scientists reported, underscoring the importance of protecting vulnerable people from the coronavirus. There’s no way to know for sure whether it was the longest-lasting Covid-19 infection because not everyone gets tested, especially on a regular basis like this case.
But at 505 days, “it certainly seems to be the longest reported infection,” said Dr. Luke Blagdon Snell, an infectious disease expert at the Guy’s and St. Thomas’ NHS Foundation Trust.